Lista Inibitori delle Monoamino Ossidasi (I-MAO)

Discussioni generiche sulle piante
Rispondi
SaulSilver
Messaggi: 333
Iscritto il: dom set 20, 2015 1:52 pm

Lista Inibitori delle Monoamino Ossidasi (I-MAO)

Messaggio da SaulSilver » mar gen 19, 2016 2:17 pm

Natural/Herbal Monoamine Oxidase Inhibitors (MAOIs)
-----------------------------------------------------------------------------------------------------------------------------------------------
Genus-Species Pseudonym(s) Active MAOI Constituent(s) Primary MAO Inhibition
-----------------------------------------------------------------------------------------------------------------------------------------------
Banisteriopsis Caapi Ayahausca, Caapi, Yage Harmala Alkaloids MAO-A
Curcuma Longa Turmeric Curcumin MAO-A
Glycyrrhiza Glabra Licorice / Liquorice Liquiritigenin, Isoliquiritigenin MAO-A/MAO-B
Nicotiana Spp. Tobacco Harmala Alkaloids MAO-A
Passiflora Incarnata Passion Flower Harmala Alkaloids MAO-A
Peganum Harmala Harmal, Syrian Rue Harmala Alkaloids MAO-A
Rhodiola Rosea Golden Root Rosavin, Rosiridin MAO-A/MAO-B
Tribulus Terrestris Puncturevine Harmala Alkaloids MAO-A/MAO-B
-----------------------------------------------------------------------------------------------------------------------------------------------
Camellia Sinensis Green Tea, Black Tea, White Tea, Oolong Tea Catechin, Epicatechin MAO-B
Coffea Spp. Coffee Harmala Alkaloids ?
Cordyceps Sinensis Caterpillar Fungus ? MAO-B
Fallopia Japonica Japanese Knotweed Emodin MAO-B
Geijera Parviflora Australian Willow ? MAO-B
Olea Europaea Olive Oil Hydroxytyrosol MAO-B
Paeonia Suffruticosa Cortex Moutan, Mudanpi, Peony Paeonol MAO-A/MAO-B
Piper Methysticum Kava Kava Desmethoxyyangonin, Methysticin MAO-B
Piper Longum Long Pepper Piperine MAO-B
Piper Nigrum Black Pepper Piperine MAO-B
Polygonum Multiflorum Fo-Ti Emodin MAO-B
Rheum Emodi Rhuharb Emodin MAO-B
Uncaria Tomentosa Cat's Claw Catechin, Epicatechin MAO-B
-----------------------------------------------------------------------------------------------------------------------------------------------
Eleutherococcus Senticosus Eleuthero, Siberian Ginseng ? ?
Hypericum Perforatum St. John's Wort ? ?
Ginkgo Biloba Ginkgo MAO-A/MAO-B ?
Ilex Paraguariensis Yerba Maté ? ?
Pausinystalia Yohimbe Yohimbe ? ?
-----------------------------------------------------------------------------------------------------------------------------------------------
Anethum Graveolens Dill Myristicin ?
Apium Graveolens Celery ? ?
Carum Carvi Caraway, Persian Cumin ? ?
Cinnamomum Verum Cinnamon ? ?
Coriandrum Sativum Coriander, Cilantro ? ?
Foeniculum Vulgare Fennel ? ?
Myristica Fragrans Nutmeg Myristicin ?
Petroselinum Crispum Parsley Myristicin ?
--------------------------------------------------------------------------------------------------------------------------------------

Alla lista aggiungo:

http://www.unige.ch/sciences/pharm/fasi ... 20IMAO.pdf

http://www.sciencedirect.com/science/ar ... 4306000047

http://www.ncbi.nlm.nih.gov/pubmed/12672993
http://www.ncbi.nlm.nih.gov/pubmed/11842339
http://www.ncbi.nlm.nih.gov/pubmed/16392662

https://examine.com/supplements/psoralea-corylifolia/
https://examine.com/supplements/eschsch ... lifornica/
https://examine.com/supplements/hordenine/

http://herbpedia.wikidot.com/monoamine-oxidase-a
http://herbpedia.wikidot.com/monoamine-oxidase-b

https://www.shroomery.org/forums/showfl ... er/4949877

https://www.visionecurativa.it/

Avatar utente
tsunami666
Messaggi: 476
Iscritto il: mer set 30, 2015 10:20 am

Re: Inibitori delle Monoamino Ossidasi (I-MAO) - Lista

Messaggio da tsunami666 » mar gen 19, 2016 3:24 pm

La liquirizia è un inibitore A e B... buono a sapersi...
Questo ce l' ho già: Hypericum Perforatum St. John's Wort
Di alzarmi non ne ho voglia,
oggi non combatto con nessuno...

Avatar utente
Triptaminico
Messaggi: 694
Iscritto il: lun set 28, 2015 7:34 pm

Re: Inibitori delle Monoamino Ossidasi (I-MAO) - Lista

Messaggio da Triptaminico » mar gen 19, 2016 3:44 pm

Grazie mille!
"Quando ricorderai chi sei, riderai di ciò che credevi di essere"

toti
Messaggi: 138
Iscritto il: dom ott 25, 2015 11:26 pm

Re: Inibitori delle Monoamino Ossidasi (I-MAO) - Lista

Messaggio da toti » ven gen 22, 2016 3:32 am

Utilissimo

Avatar utente
spiritualconnection
Messaggi: 367
Iscritto il: mer nov 25, 2015 4:35 am

Re: Inibitori delle Monoamino Ossidasi (I-MAO) - Lista

Messaggio da spiritualconnection » lun apr 11, 2016 8:36 pm

Sarebbe possibile avere una lista ordinata in base alla efficacia ?
Voglio dire ... come si fa a sapere quanto è potente la liquirizia rispetto alla passiflora per esempio ?

Vi segnalo inoltre la Uncaria Rhynchophylla che sarebbe una parente prossima della Uncaria Tomentosa o anche volgarmente chiamata "artiglio di gatto" che pare sia molto efficace associata alla Quercitina.

http://www.livestrong.com/article/82970 ... -activity/

In ogni caso, grazie ... info utilissime.
Ultima modifica di spiritualconnection il lun apr 11, 2016 8:59 pm, modificato 1 volta in totale.
---
We are fractal extensions of the transcendent consciousness. We collectively create an infinite spectrum of symphonies, of vibration for the purpose of experience. We are the Universe perceiving itself, and thus creating itself
Ryan Boyd

Avatar utente
spiritualconnection
Messaggi: 367
Iscritto il: mer nov 25, 2015 4:35 am

Re: Inibitori delle Monoamino Ossidasi (I-MAO) - Lista

Messaggio da spiritualconnection » lun apr 11, 2016 8:55 pm

Riporto info prese da drugs-forum.com :
  • -turmeric (active compound curcumin) ---[only when taken with piperine, a.k.a. black pepper, piperine slows down curcumin metabolism](reversibly inhibits MAO-A and MAO-B) "140 to 560 mg/kg for 14 days, were able to elicit dose-dependent relation of immobility reduction in the tail suspension test and the forced swimming test in mice. The effects of the extracts at the dose of 560 mg/kg were more potent than that of reference antidepressant fluoxetine. The extracts, at the dose of 140 mg/kg or above for 14 days, significantly inhibited the monoamine oxidize A (MAO) activity in mouse whole brain at a dose-dependent manner, however, oral administration of the extract only at a dose of 560 mg/kg produced observable MAO B inhibitory activity in animal brain"

    -Geiparvarin, a substance in the Australian Willow, MAO-B inhibitor

    -catechin / catechins, found in green Tea, and tons of other fruits/vegetables/random stuff, ..MAO-B inhibitor

    -cats Claw (Uncaria tomentosa) contains Catechin, epicatechin, and other compounds, ..MAO-B inhibitor(s)

    -harmaline (strong reversible inhibitor of MAO-A, questionable inhibition of MAO-B), found in Syrian Rue, Banisteriopsis Caapi and many other amazonian plants. can cause NAUSEA, anxiety, and hallucinations.

    -passion flower (very weak, questionable efficacy, probably due to content of harmaline alkaloids)

    -emodin, a substance in rhubarb stalks (not in leaves, the leaves are poisonous) ,... also found in Japanese Knotweed (inhibition of MAO-B, however emodin also increases estrogenic activity)

    -coffee (most commonly exibits weak non-selective inhibition, due to harmaline alkaloids. highest levels of these alkaloid are found in ready to drink (instant) coffee)

    -wild green oats (a.k.a. oats, but some differences exist) have been shown to have some inhibitory activity upon MAO-B enzymes. this is questionable, only a few studies have been done on it. however, oats have been proven to raise levels of free testosterone in the body, many studies have confirmed oats as having aphrodisiac properties.

    -Syrian Rue, also Banisteriopsis Caapi, (contain harmaline alkaloids, very potent MAO-A inhibitor, can cause hallucinations, and vomiting)

    -Kaempferol, a substance found in onions, teas, broccoli, strawberries, and tons of other stuff (google it) has been shown to have potent MAO-A inhibition.

    -Apigenin, a citrus bioflavonoid, also found in several herbs including chamomile, parsley, thyme, celery, and mugwort, has shown potent MAO-A inhibitory activity. One micromole (uM) of apigenin inhibited 50% of mouse brain MAO.

    -Piperine, the principal chemical responsible for spicyness in black pepper, has shown weak MAO-A and MAO-B inhibitory properties. However, piperine should be taken in caution, because it can significantly slow the metabolism of many drugs, causing body levels of the drug to increase greatly.....

    -red yeast rice posesses potent MAO-A and MAO-B inhibitory properties.

    -quercetin = MAO-A inhibition, weaker MAO-B inhibition.

    -Maclura tricuspidata (active ingredient "gancaonin A") = potent MAO-B inhibition, lesser MAO-A inhibition

    -red clover, containing Formononetin, strongly inhibited MAO-A and B.

    -Sophora flavescens, a chinese plant, posesses strong inhibition of MAO-A and B, this plant also supresses substance P, and has a putative agonist activity at mu and kappa opioid receptors .

    -rhubarb
---
We are fractal extensions of the transcendent consciousness. We collectively create an infinite spectrum of symphonies, of vibration for the purpose of experience. We are the Universe perceiving itself, and thus creating itself
Ryan Boyd

SaulSilver
Messaggi: 333
Iscritto il: dom set 20, 2015 1:52 pm

Re: Inibitori delle Monoamino Ossidasi (I-MAO) - Lista

Messaggio da SaulSilver » lun apr 11, 2016 9:26 pm

Caffeina Ki hMAO-B = 3.83 mM , anche lei è un MAO-B inibitore. Non mi sorprende affatto. DOPAMINA <3

THC: IC50 pMAO-B = 22.6 μM (anche la nostra erba :weed: è un leggero MAO)

Methylpiperate (contenute nel pepe nero e pepe lungo) IC50 rMAO-B = 1.6 μM,
Ki rMAO-B = 1.3 μM

Norharmane: IC50 hMAO-B = 4.68 μM, (contenuta nel caffè) <3
Ki hMAO-B = 1.12 μM

Scopoletina: MAO-B

Link al pdf:
http://link.springer.com/article/10.100 ... 013-9490-6
http://www.unige.ch/sciences/pharm/fasi ... 20IMAO.pdf

Avatar utente
spiritualconnection
Messaggi: 367
Iscritto il: mer nov 25, 2015 4:35 am

Re: Inibitori delle Monoamino Ossidasi (I-MAO) - Lista

Messaggio da spiritualconnection » lun apr 11, 2016 10:05 pm

E nel caso di tintura madre o estratto come ci si regola quindi ?
---
We are fractal extensions of the transcendent consciousness. We collectively create an infinite spectrum of symphonies, of vibration for the purpose of experience. We are the Universe perceiving itself, and thus creating itself
Ryan Boyd

Rispondi